Publications (2007 – 2013)



Myerson, A.S., and Trout, B.L., (2013). Nucleation from Solution. Science 341, 855-856. Link

Shi, X., Wong, S.Y., Yang, X., and Myerson, A.S., (2013). Concomitant Cocrystallization on Engineered Surfaces. CrystEngComm 15, 7450- 7455. Link

Mascia, S., Heider, P.L., Zhang, H., Lakerveld, R., Benyahia, B., Barton, P.I., Braatz, R.D., Cooney, C.L., Evans, J.M.B., Jamison, T.F. Jensen, K.F., Myerson, A.S., and Trout, B.L., (2013). End-to-End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation. Angewandte Chemie International Edition, Vol. 52, Issue 47, 12359-12363. Link

Atkinson,, M.B.J., Bwambok, B.K., Chen, J., Chopode, P.D., Thuo, M.M., Mace, C.R., Mirica, K.A., Kumar, A.A., Myerson, A.S., Whitesides, G.M., (2013). Using Magnetic Levitation to Separate Crystals of Polymorphs. Angewandte Chemie International Edition (published on web). Link

Wang, H., Gurau, G., Kelley, S.P., Myerson, A.S., Rogers, R.D., (2013). Hydrophobic vs. Hydrophilic Ionic Liquid Separations Strategies in Support of Continuous Pharmaceutical Manufacturing. RSC Advances 3, 10019-10026. Link

Hsi, K., Concepcion , A.J., Kenny, M., Magzoub, A.A, Myerson, A.S., (2013). Purification of Amoxicillin Trihydrate by Impurity-Coformer Complexation in Solution. CrystEng Comm. 15, 6776-6781. Link

López-Mejías, V., Myerson, A.S., Trout, B.L., (2013). Geometric Design of Heterogeneous Nucleation Sites on Biocompatible Surfaces. Crystal Growth and Design 13. 3835-3841. Link

Zhou, L., Su, M., Benyahia, B., Singh, A.,  Barton, P.I., Trout, B.L., Myerson, A.S.,and Braatz, R.L. (2013). Mathematical Modeling and Design of Layer Crystallization in a Concentric Annulus with and without Recirculation.  AICHE J, Vol. 59, Issue 4, 1308-1321. Link

Quon, J.L., Chadwick, K., Wood, G.P.F., Sheu, I., Brettmann, B.K ., Myerson, A.S., Trout, B.L. (2013).  Templated Nucleation of Acetaminophen on Spherical Excipient Agglomerates.  Langmuir2013, 29(10), pp 3292-3300. Link

Brettmann, B.K.,  Cheng, K., Myerson, A.S., Trout, B.L., (2013). Electrospun formulations containing crystalline active pharmaceutical ingredients. Pharmaceutical Research 1, 238-246. Link

Hsi, K.,  Kenny, M., Simi, A., Myerson, A.S., (2013).  Purification of Structurally Similar Compounds by the Formation of Impurity Co – former Complexes in Solution.  Crystal Growth and Design2013, 13(4), pp 1577-1582. Link

Wong, S.Y., Chen, J., Forte, L and Myerson, A.S., (2013). Compact Crystallization, Filtration and Drying for the Production of Active Pharmaceutical Ingredients. Organic Process Research and Development, 2013 17(4), pp 684-692Link

Wong, S.Y., Cui, Y., and Myerson, A.S., (2013). Contact Secondary Nucleation as a Means of Creating Seeds for Continuous Tubular Crystallizers. Crystal Growth and Design 13, 2514-2521. Link



Chadwick, K, Chen, J, Myerson, A.S., and Trout, B.L. (2012).  Toward the Rational Design of Crystalline Surfaces for Heteroepitaxy: Role of Molecular Functionality.  Crystal Growth and Design  12, 1159-1166. Link

Diao, Y., Whaley, K.E.,  Helgeson, M.E., Woldeyes, M.A., Doyle, P.S., Myerson, A.S.,  Hatton, T.A., and Trout, B.L. (2012). Gel Induced Selective Crystallization of Polymorphs.  JACS 134, 673-684. Link

Brettman, B., Bell, E., Myerson, A.S., and Trout, B.L. (2012).  Solid state NMR characterization of high-loading solid solutions of API and excipients formed by electrospinning. J. Pharm. Sci101, 1538-1545. Link

Zhang, H., Quon, J.,  Alvarez, A., ; Evans, J.M.,  Myerson, A.S., and Trout, B.L.  (2012). Development of Continuous Anti-solvent-cooling Crystallization Process Using Cascaded MSMPR Crystallizer. Organic Research Process and Development  16, 915-924. Link

Hsi, H.Y., Chadwick, K., Fried, A, Kenny, M., and Myerson, A.S. (2012).  Separation of Impurities from Solution by Selective Co-Crystal Formation. Cryst. Eng. Comm.  14, 2386-2388. Link

Brettmann, B.K., Tsang, S., Forward, K.M.,  Rutledge, G.C., MyersonA.S., and Trout, B.L. (2012).  Free Surface Electrospinning of Fibers Containing Nanoparticles.  Langmuir 28, 9714-9721. Link

Brettmann, B.K., Myerson, A.S., and Trout, B.L. (2012).  Solid State Nuclear Magnetic Resonance Study of the Physical Stability of Electrospun Drug and Polymer Solid Solutions.  J. Pharm. Sci. 101, 2185-2193. Link

Quon, J.L., Zhang,H., Alvarez, A., Evans, J.M.,  Myerson, A.S., Trout, B.L., (2012).  Continuous Crystallization of Aliskiren Hemifumarate. Crystal Growth and Design 12, 3036-3044. Link

Zaworotko, M.J., Aitipamula, S.,  Banerjee, R.,  Bansal, A.K., Biradha, K., Cheney,  M. Roychoudhury, A.,  Desiraju, D., Dikundwar, A., Dubey, R., Duggirala, N., Ghogale,  P., Ghosh,  S., Goswami, P.K. Goud, R.,  Jetti, R.,  Karpinski, P., Kaushik, P., Shukla, D.S., Kumar, V., Moulton, B., Mukherjee, A., Mukherjee, G., Myerson, A.S, Rajamannar, T., Ramanan, A.,  Reddy, C.M., Rodríguez-Hornedo, N., Rogers, R.D., Narasingarao, T., Row, T., Sanphui, P., Shan, N., Shete, G., Singh, A., Sun, C.C.,  Swift, J.A., Thaimattam, R., Singh, Thakur, T.S., Thaper, R.K., Thomas, S.P., Tothadi, S., Vangala, V.R., Variankaval, N., Peddy,  V., Weyna, D. (2012).  Polymorphs Salts and Cocrystals:  What’s in a Name?  Crystal Growth and Design 12, 2147-2152. Link

Chen, J., and Myerson, A.S. (2012).  Pasteur Revisited: Chiral Separation by Crystallization on Self-Assembled Monolayers.  Cryst Eng Communications 14, 8326-8329. Link

Yang, X., Sarma, B., and Myerson, A.S., (2012).  Polymorph Control of Micro/Nano Sized Mefenamic Acid Crytals on Patterned Self Assembled Monolayers. Crystal Growth and Design 12, 5521-5528. Link

Wong, S.Y., Tatusko, A., Trout, B.L., and Myerson, A.S.  (2012). Development of Continuous Crystallization Processes Using a Single Stage MSMPR Crystallizer with Recycle. Crystal Growth and Design 12, 5701-5707. Link

Diao, Y., Hegelson, M.E., Siam, Z.A., Doyle, P.S., Myerson, A.S., Hatton, T. A., and Trout, B.L. (2012). Nucleation under Soft Confinement: Role of Polymer-Solute Interactions. Crystal Growth and Design 12, 508-517. Link

Wang, M., Rutledge, G.C., Myerson, A.S., and Trout, B.L. (2012). Production and Characterization of Carbamezapine Nanocrystals by Electrospraying. J. Pharm. Sci. 101, 1178-1188. Link



Chen, J., Sarma, B., Evans, J.M.B., and Myerson, A.S. (2011). Pharmaceutical Crystallization. Crystal Growth and Design 11, 887-895. Link

Diao, Y., Myerson, A.S., Hatton, T.A., and Trout, B. L. (2011). Surface Design for Controlled Crystallization: The Role of Surface Chemistry and Nanoscale Pores in Heterogeneous Nucleation. Langmuir 27, 5324-5334. Link

Diao, Y., Hegelson, M.E., Myerson, A. S., Hatton, T. A.,  Doyle, P. S., and Trout, B.L.  (2011).  Controlled Nucleation from Solution Using Polymer Microgels.  Journal of the American Chemical Society 133, 3756-3759. Link

Lee, A.Y., Erdemir, D, Myerson, A.S. (2011). Crystal Polymorphism in Chemical Process Development. The Annual Review of Chemical and Biomolecular Engineering 2, 259-280. Link

Diao, Y., Harada, T., Myerson, A.S., Hatton, T.A., and Trout. B.L. (2011). The Role of Pore Shape on Surface-Induced Crystallization. Nature Materials 10, 867-871. Link

Antwi, M., Myerson, A.S., and Zurawsky, W. (2011). Diffusion of Lysozyme in Buffered Salt Solutions. Industrial and Engineering Chemistry Research 50, 10313-10319. Link

Alvarez, A., Singh, A., and Myerson, A.S. (2011). Crystallization of Cyclosporine in a Continuous Multistage MSMPR Crystallizer. Crystal Growth and Design 11, 4392-4400. Link

Chadwick, K, Myerson, A.S., and Trout, B.L. (2011). Polymorph Control by Heterogeneous Nucleation – A New Method of Selecting Crystalline Substrates. Cryst. Eng. Comm. 13, 6625-6627. Link

Chadwick, K, Chen, J, Myerson, A.S., and Trout, B.L. (2011). Toward the Rational Design of Crystalline Surfaces for Heteroepitaxy: Role of Molecular Functionality. Crystal Growth and Design, 12, 1159-1166. Link

Hsi, H.Y., Chadwick, K., Fried, A, Kenny, M., and Myerson, A.S. (2011). Separation of Impurities from Solution by Selective Co-Crystal Formation. Cryst. Eng. Comm. 14(7), 2386-2388. Link

Lee, S., Choi, A., Kim, W.S., and Myerson, A.S. (2011). Phase Transformation of Sulfamerazine using a Taylor Vortex. Crystal Growth and Design 11, 5019-5029. Link

Chen J., Sarma B., Evans J. M.B., and Myerson A.S. (2011) Pharmaceutical Crystallization. Crystal Growth and Design (published on web). Link

Sarma B., Chen J., Hsi, H.Y., and Myerson A.S. (2011) Solid forms of pharmaceuticals: Polymorphs, salts and cocrystals. Korean Journal of Chemical Engineering, 28, 315-322. Link

Kim, K, Centrone, A., Hatton, T.A., and Myerson, A.S. (2011) Polymorphism control of nanosized glycine crystals on engineered surfaces. Cryst. Eng. Comm. 13, 1127-1131. Link



Singh, A. and Myerson, A.S. (2010). Chiral Self Assembled Monolayers as Resolving Auxiliaries in the Crystallization of Valine. Journal of Pharmaceutical Science 99, 3931-3940. Link

Alvarez, A. and Myerson, A.S. (2010). Continuous Plug Flow Crystallization of Pharmaceutical Compounds. Crystal Growth and Design 10, 2219-2228. Link



Kim, K, Lee, I.S., Centrone, A., Hatton, T.A. and Myerson, A.S. (2009). Formation of Nanosized Organic Molecular Crystals on Engineered Surfaces. Journal of the American Chemical Society 131, 18212-18213. Link

Alvarez, A., Sing, A., and Myerson, A.S. (2009). Polymorph Screening: Comparing a Semi-Automated Approach with a High Throughput Method. Crystal Growth and Design 9, 4181-4188. Link

Aldabaibeh, N., Jones, M., Myerson, A.S., Ulrich, J. (2009). The Solubility of Orthorhombic Lysozyme Crystals Grown at High pH. Crystal Growth and Design 9, 3313-3317. Link

Erdemir, D, Lee, A.Y., and Myerson, A.S. (2009). Nucleation of Crystals From Solution: Classical and Two Step Models. Accounts of Chemical Research 42, 621-629. Link

Singh, A., Lee, I.S., and Myerson, A.S. (2009). Concomitant Crystallization of ROY on Patterned Substrates: Using a High Throughput Method to Improve the Chances of Crystallization of Different Polymorphs. Crystal Growth and Design 9, 1182-1185. Link



Konkel, J.T., and Myerson, A.S. (2008). Empirical Molecular Modeling of a Suspension Stabilization Using Polysorbate 80. Molecular Simulation 34, 1353-1357. Link

Lee, I.S., Evans, J.M.B., Erdemir, D., Lee, A.Y., Garetz, B.A and Myerson, A.S., (2008). Non Photochemical Laser Induced Nucleation of Hen White Lysozyme Crystals. Crystal Growth and Design 8, 4455-4461. Link

Sun, X., Garetz, B.A., and Myerson, A.S., (2008). Polarization Switching of Crystal Structure in the Non-Photochemical Laser Induced Nucleation of Supersaturated Aqueous L-Histidine. Crystal Growth and Design 8, 1720-1722. Link

Lee, I.S., Kim, K.T., Lee, A.Y. and Myerson, A.S., (2008). Concomitant Crystallization of Glycine on Patterned Substrates: The Effect of pH on the Polymorphic Outcome. Crystal Growth and Design, 8, 108-113. Link

Lee, I.S., Lee, A.Y., and Myerson, A.S., (2008). Concomitant Polymorphism in Confined Environment: Implication to Crystal Form Screening. Pharmaceutical Research, 25, 960-968. Link



Erdemir, D., Lee, A.Y., and Myerson, A.S., (2007). Polymorph Selection: The Role of Nucleation, Crystal Growth and Molecular Modeling. Current Opinion in Drug Discovery and Development, 10, 746-755. Link

Erdemir, D., Chattopadhyay, S., Guo, L., Ilavsky, J., Amentitsh, H., Segre, and Myerson, A.S. (2007). Relationship Between Self-Association of Glycine Molecules in Supersaturated Solutions and Solid State Outcome. Physical Review Letters, 99, 115702. Link