Publications (2020 – Present)

2024

2024

Aprile G., Pandit A.V., Albertazzi J., Vetter T., Viano R., Milani L., Adamo A., Myerson A.S., Stelzer T. (2024) Residence Time Distribution Characterization and Proof-of-Concept of a Novel Stacked 7-Stage Continuous Crystallizer Cascade with Diaphragm-Driven Slurry Transfer. Industrial & Engineering Chemistry Research 63 (42), 18199-18211. Link

Zhang Q., Pandit A., Liu Z., Guo Z., Muddu S., Wei Y., Pereg D., Nazemifard N., Papageorgiou C., Yang Y., Tang W., Braatz R.D., Myerson A.S., Barbastathis G. (2024) Non-invasive estimation of the powder size distribution from a single speckle image. Light: Science & Applications 13 (1), 200. Link

Zimmermann L., Lee H.L, Koishybay A.,  Vlaar C.P, Monbaliu J.C.M., Romañach R.J., Noor-E-Alam Md., Myerson A.S., Stelzer T. (2024) Measurements and Correlation of Timolol Maleate Solubility in Biobased Neat and Binary Solvent Mixtures. Journal of Chemical & Engineering Data. Link

Fellah N., Dela Cruz I.J.C., Alamani B.G., Shtukenberg A.G., Pandit A.V., Ward M.D., Myerson A.S. (2024) Crystallization and Polymorphism under Nanoconfinement. Crystal Growth & Design 24 (8), 3527-3558. Link

Østerby J.M., Topalian S.O.N., Jacobsen M.F., Skovby T., Gernaey K.V., Myerson A.S., Woodley J. (2024) Raman spectroscopy and one-dimensional convolutional neural network modeling as a real-time monitoring tool for in vitro transaminase-catalyzed synthesis of a pharmaceutically relevant amine precursor. Biotechnology Progress, e3444. Link

Eren A., Ali J.A., Ma W., de Moraes M.G.F., Weerakkodige D.R.R., Myerson A.S. (2024) Influence of Volume on the Nucleation of Polymorphic Molecules Through an Induction Time Approach–Part II. Crystal Growth & Design 24 (6), 2452-2461. Link

Devos C., Mukherjee S., Inguva P., Singh S., Wei Y., Mondal S., Yu H., Barbastathis George, Stelzer T., Braatz R.D., Myerson A.S. (2024). Impinging jet mixers: A review of their mixing characteristics, performance considerations, and applications. AIChE Journal, e18595. Link

Bolla G., Nayak A., Chatel G., Debbeti V., Hines C.C., Kelley S.P,  Vaid T.P.,  Myerson A.S., Rogers R.D. (2024). Novel strategies for terephthalic acid processing under soft conditions using ionic liquids. Journal of Ionic Liquids, 4(1), 100079. Link

2023

2023

Aprile, G., Pandit, A. V., Albertazzi, J., Eren, A., Capellades, G., Thorat, A. A., Gamekkanda, J. C., Vetter, T., Skovby, T., Sin, G., Wu, H., Dam-Johansen, K., Myerson, A.S. (2023). Loop-Configuration for Plug Flow Crystallization Process Development. Crystal Growth & Design, 23(11), 8052–8064. Link

Zhang, Q., Gamekkanda, J. C., Pandit, A., Tang, W., Papageorgiou, C., Nazemifard, N., Yang, Y., Schwaerzler, M., Oyetunde, T., Braatz, R. D., Myerson, A.S., Barbastathis, G. (2023). Quantitative Speckle Analysis to Estimate Surface Particle Size Distribution. Optica Imaging Congress (3D, COSI, DH, FLatOptics, IS, PcAOP), CW5B.4. Link

Barbastathis, G., Zhang, Q., Pandit, A., Tang, W., Papageorgiou, C., Braatz, R., Myerson, A.S., Tan, B., Schmetterer, L. (2023). On the use of physics in machine learning for manufacturing process inspection. In P. Ferraro, S. Grilli, & D. Psaltis (Eds.), Optical Methods for Inspection, Characterization, and Imaging of Biomaterials VI (Issue August 2023, p. 60). SPIE. Link

Srisuma, P., Pandit, A., Zhang, Q., Hong, M. S., Gamekkanda, J., Fachin, F., Moore, N., Djordjevic, D., Schwaerzler, M., Oyetunde, T., Tang, W., Myerson, A.S., Barbastathis, G., Braatz, R. D. (2023). Thermal imaging-based state estimation of a Stefan problem with application to cell thawing. Computers and Chemical Engineering, 173(February), 108179. Link

Zhang, Q., Gamekkanda, J. C., Pandit, A., Tang, W., Papageorgiou, C., Mitchell, C., Yang, Y., Schwaerzler, M., Oyetunde, T., Braatz, R. D., Myerson, A.S., Barbastathis, G. (2023). Extracting particle size distribution from laser speckle with a physics-enhanced autocorrelation-based estimator (PEACE). Nature Communications, 14(1), 1–9. Link

de Moraes, M. G. F., Barreto, A. G., Secchi, A. R., de Souza, M. B., Lage, P. L. da C., Myerson, A.S. (2023). Polymorphism of Praziquantel: Role of Cooling Crystallization in Access to Solid Forms and Discovery of New Polymorphs. Crystal Growth and Design, 23(2), 1247–1258. Link

Scott, D., Briggs, N. E. B., Formosa, A., Burnett, A., Desai, B., Hammersmith, G., Rapp, K., Capellades, G., Myerson, A.S., Roper, T. D. (2023). Impurity Purging through Systematic Process Development of a Continuous Two-Stage Crystallization. Organic Process Research and Development, 27(1), 148–158. Link

Eren, A., Civati, F., Ma, W., Gamekkanda, J. C., Myerson, A.S. (2023). Continuous crystallization and its potential use in drug substance Manufacture : A review.Journal of Crystal Growth, 601 (May 2022), 126958. Link

2022

2022

Capellades, G.; Bonsu, J. O.; Myerson, A.S.  (2022) Impurity Incorporation in Solution Crystallization: Diagnosis, Prevention, and Control. CrystEngComm24 (11), 1989–2001. Link

2021

2021

Bagi, S.D., Myerson, A.S., Román-Leshkov, Y. (2021). Solvothermal Crystallization Kinetics and Control of Crystal Size Distribution of MOF-808 in a Continuous Flow Reactor Crystal Growth & Design 21 (11), 6529-6536 Link

Capellades, G.,  Neurohr, C., Briggs, N., Rapp, K., Hammersmith, G., Brancazio, D., Derksen, B., Myerson, A.S. (2021). On-Demand Continuous Manufacturing of Ciprofloxacin in Portable Plug-and-Play Factories: Implementation and In Situ Control of Downstream Production Org. Process Res. Dev. 2021, 25, 7, 1534–1546 Link

Myerson, A.S., Azad, M.A., Hammersmith, G.J., Brancazio, D., Caicedo, J.G.O. (2021). Systems and methods for the fabrication of tablets, including pharmaceutical tablets US Patent 11,020,352 Link

Mozdzierz, N. J., Lee, Y.,  Hong, M.S., Benisch,M.HP., Rasche,M. L., Tropp, U.E.,  Jiang, M., Myerson, A.S., Braatz, R. D. (2021). Mathematical Modeling and Experimental Validation of Continuous Slug-flow Tubular Crystallization with Ultrasonication-induced Nucleation and Spatially Varying Temperature Chemical Engineering Research and Design Link

Dela Cruz, I. J. C., Perez, J. V., Alamani, B. G.,  Capellades, G.,  Myerson, A.S. (2021). Influence of Volume on the Nucleation of Model Organic Molecular Crystals through an Induction Time Approach Crystal Growth & Design Link

Azad, M. A.,  Capellades, G., Wang, A. B., Klee, D. M.,  Hammersmith, G., Rapp, K., Brancazio, D.,  Myerson, A.S. (2021). Impact of Critical Material Attributes (CMAs)-Particle Shape on Miniature Pharmaceutical Unit Operations AAPS PharmSciTech Link

2020

2020

Rogers, L., Briggs, N., Achermann, R., Adamo, A., Azad, M., Brancazio, D., Capellades, G., Hammersmith, G., Hart, T., Imbrogno, J., Kelly, L.P., Liang, G., Neurohr, C., Rapp, K., Russell, M.G., Salz, C., Thomas, D.A., Weimann, L., Jamison, T.F., Myerson, A.S., Klavs F Jensen (2020). Continuous Production of Five APIs in Flexible Plug-and-Play Modules: A Demonstration Campaign. Organic Process Research & Development Link

Capellades, G., Neurohr, C., Azad, M., Brancazio, D., Rapp, K., Hammersmith, G., Myerson, A.S. (2020). A Compact Device for the Integrated Filtration, Drying, and Mechanical Processing of Active Pharmaceutical Ingredients. Journal of Pharmaceutical Sciences 109 (3), 1365-137 Link

Stelzer, T.; Lakerveld, R.; Myerson, A.S. (2020) Process Intensification in Continuous Crystallization. In The Handbook of Continuous Crystallization; Yazdanpanah, N., Nagy, Z. K., Eds.; Royal Society of Chemistry; pp 266–320. Link