Recent Publications (2016 – current)

Capellades, G., Neurohr, C., Azad, M., Brancazio, D., Rapp, K., Hammersmith, G., Myerson, A.S. (2019). A Compact Device for the Integrated Filtration, Drying, and Mechanical Processing of Active Pharmaceutical Ingredients. Journal of Pharmaceutical Sciences 109 (3), 1365-1372 Link

Azad, M., Osorio, J.G., Wang, A., Klee, D.M., Eccles, M.E., Grela, E., Sloan, R., Hammersmith, G., Rapp, K., Brancazio, D., Myerson, A.S. (2019). On-Demand Manufacturing of Direct Compressible Tablets: Can Formulation Be Simplified? Pharmaceutical Research 36 (12), 167 Link

Schall, J.M., Capellades, G., Myerson, A.S. (2019). Methods for estimating supersaturation in antisolvent crystallization systems. CrystEngComm 21 (38), 5811-5817 Link

Schall, J.M., Capellades, G., Mandur, J.S., Braatz, R.D., Myerson, A.S. (2019). Incorporating Solvent-Dependent Kinetics To Design a Multistage, Continuous, Combined Cooling/Antisolvent Crystallization Process. Organic Process Research & Development 23 (9), 1960-1969 Link

Capellades, G., Wiemeyer, H., Myerson, A.S. (2019). Mixed-Suspension, Mixed-Product Removal Studies of Ciprofloxacin from Pure and Crude Active Pharmaceutical Ingredients: The Role of Impurities on Solubility and Kinetics. Crystal Growth and Design 19 (7), 4008-4018 Link

Berton, P., Mishra, M.K., Choudhary, H., Myerson, A.S., Rogers, R.D. (2019). Solubility Studies of Cyclosporine Using Ionic Liquids. ACS Omega 4 (5), 7938-7943 Link

Nicoud, L., Licordari, F., Myerson, A.S. (2019). Polymorph control in MSMPR crystallizers. A case study with paracetamol. Organic Process Research & Development 23 (5), 794-806 Link

Wijethunga, T.K., Chen, X., Myerson, A.S., Trout, B.L. (2019). The use of biocompatible crystalline substrates for the heterogeneous nucleation and polymorphic selection of indomethacin. CrystEngComm 21, 2193-2202 Link

Nicoud, L., Licordari, F., Myerson, A.S. (2019). Polymorph control in batch seeded crystallizers. A case study with paracetamol. CrystEngComm 21, 2105-2118 Link

Tahara, K., Kono, Y., Myerson, A.S., Takeuchi, H. (2018). Development of continuous spherical crystallization to prepare fenofibrate agglomerates with impurity complexation using MSMPR crystallizer. Crystal Growth and Design 18 (11), 6448-6454 Link

Bolla, G., Myerson, A.S. (2018). SURMOF induced morphological crystal engineering of the substituted benzamides. Crystal Growth and Design 18 (11), 7048-7058 Link

Nicoud, L., Licordari, F., Myerson, A.S. (2018). Estimation of the solubility of metastable polymorphs- a critical review. Crystal Growth and Design 18 (11), 7228-7237 Link

Wijethunga, T.,  Stojakovic, J., Bellucci, M., Chen, X., Myerson, A.S., Trout, B. (2018). General method for the identification of crystal faces using Raman spectroscopy combined with machine learning and application to the epitaxial growth of acetaminophen. Langmuir 34 (33), 9836-9846 Link

Tow, E., Myerson, A.S. et. al. (2018). Comparison of fouling propensity between reverse osmosis, forward osmosis and membrane distillation. Journal of Membrane Science 556, 352-364 Link

Pons-Siepermann, C, Myerson, A.S. (2018). Inhibition of nucleation using a dilute, weakly hydrogen-bonding molecular additive. Crystal Growth & Design 18 (6), 3584-3595 Link

Azad, M., Myerson, A.S. et. al. (2018). A compact, portable,re-configurable and automated system for on-demand pharmaceutical tablet manufacturing. International journal of pharmaceutics 539 (1-2), 157-164 Link

Zhang, P., Myerson, A.S. et. al. (2018). Advanced continuous flow platform for on-demand pharmaceutical manufacturing. Chemistry–A European Journal 24 (11), 2776-2784 Link

Schall, J., Mandur, J., Braatz, R.D., Myerson, A.S. (2018). Nucleation and growth kinetics for combined cooling and antisolvent crystallization in a mixed-suspension, mixed-product removal system: estimating solvent dependency. Crystal Growth & Design 18 (3), 1560-1570 Link

Puri, V., Brancazio, D., Harinath, E., Martinez, A.R., Desai, P.M., Jensen, K.D., Chun, J., Braatz, R.D., Myerson, A.S., Trout, B.L. (2018). Demonstration of pharmaceutical tablet coating process by injection molding technology. International Journal of Pharmaceutics 535 (1-2), 106-112 Link

Vartak, S., Dwyer, L., Myerson, A.S. (2018). Surface functionalization in combination with confinement for crystallization from undersaturated solutions. CrystEngComm Link

A Mukherjee, A., Rogers, R., Myerson, A.S. (2018). Cocrystal formation by ionic liquid-assisted grinding: case study with cocrystals of caffeine. CrystEngComm Link

Badruddoza, P., Gupta, A., Myerson, A.S. , Trout, B.L., Doyle,P. (2018). Low energy nanoemulsions as templates for the formulation of hydrophobic drugs. Advanced Therapeutics Link

Bolla, G., Myerson, A.S. (2018). SURMOF induced polymorphism and crystal morphological engineering of acetaminophen polyporphs: advantage of heterogeneous nucleation. CrystEngComm 20 (15), 2084-2088 Link

Choudhary,H., Berton, P., Gurau, G., Myerson, A.S. , Rogers,R. (2018). Ionic liquids in cross-coupling reactions: “liquid” solutions to a “solid” problem. Chemical Communications 54 (16), 2056-2059 Link

Zeng, Q., Mukherjee, A., Muller, P., Rogers, R., Myerson, A.S. (2018). Exploring the role of ionic liquids to tune polymorphic outcome of organic compounds. Chemical Science 9 (6), 1510-1520 Link

Puri,V., Brancazio, D., HarinathE.,MartinezA., Desai,P.,Jensen,K.,Chun,J-H.,Braatz,K., Myerson, A.S. Trout, B.L. (2018). Demonstration of pharmaceutical tablet coating process by injection molding technology. International Journal of Pharmaceutics 535 (1),106-112 Link

Vartak, S., Myerson, A.S. (2017). Complexation-assisted Continuous Crystallization of Isomeric Systems with Nanofiltration Recycle.Crystal Growth & Design Link

Desai, P.M., Hogan, R.C., Brancazio, D., Puri, V., Jensen, K.D., Chun, J-H., Myerson, A.S., Trout, B.L. (2017). Integrated hot-melt extrusion− injection molding continuous tablet manufacturing platform: Effects of critical process parameters and formulation attributes on product robustness and dimensional stability. International Journal of Pharmaceutics 531 (1), 332-342 Link

Puri, V., Brancazio, D., Desai, P.M., Jensen, K.D., Chun, J-H., Myerson, A.S., Trout, B.L. (2017). Development of Maltodextrin Based Immediate Release Tablets using an Integrated Twin-Screw Hot Melt Extrusion and Injection Molding Continuous Manufacturing Process. Journal of Pharmaceutical Sciences Link

Wijethunga, T.K., Baftizadeh, F., Stojakovic, J., Myerson, A.S., Trout, B.L. (2017).  Experimental and mechanistic study of the heterogeneous nucleation and epitaxy of acetaminophen with biocompatible crystalline substrates. Crystal Growth & Design 17 (7), 3783–3795 Link

Yazdanpanah, N., Testa, C.J., Perala, S., Jensen, K.D., Braatz, R.D., Myerson, A.S., Trout, B.L. (2017). Continuous Heterogeneous Crystallization on Excipient Surfaces. Crystal Growth & Design 17 (6), 3321–3330 Link

Stojakovic, J., Baftizadeh, F., Bellucci, M., Myerson, A.S., Trout, B.L. (2017). Angle-directed nucleation of paracetamol on biocompatible nano-imprinted polymers. Crystal Growth & Design 17 (6), 2955–2963 Link

Dwyer, L., Kulkarni,S., Ruelas, L., Myerson, A.S. (2017). Two-Stage Crystallizer Design for High Loading of Poorly Water-Soluble Pharmaceuticals in Porous Silica Matrices. Crystals 7 (5), 131 Link

Capellades, G., Kiil, S., Dam-Johansen, K., Mealy, M.J., Christensen, T.V, Myerson, A.S. (2017). Effect of Air Injection on Nucleation Rates: An Approach from Induction Time Statistics. Crystal Growth & Design 17 (6), 3287-3294 Link

Kunov‐Kruse, A.J., Weber, C.C., Rogers, R.D., Myerson, A.S. (2017). The A Priori Design and Selection of Ionic Liquids as Solvents for Active Pharmaceutical Ingredients. Chemistry A European Journal 23 (23) 5498- 5508 Link

Pons-Siepermann, C.A., Huang, S., Myerson, A.S. (2017). Nucleation Inhibition of Benzoic Acid through Solution Complexation. Crystal Growth & Design 17 (5),2646-2653 Link

Vartak, S., Myerson, A.S. (2017). Continuous Crystallization with Impurity Complexation and Nanofiltration Recycle. Organic Process Research & Development  21 (2), pp 253–261 Link

Li, J., Lai, T.T.C., Trout, B.L., Myerson, A.S. (2017). Continuous Crystallization of Cyclosporine: the Effect of Operating Conditions on Yield and Purity. Crystal Growth & Design Link

Kulkarni, S.A., Myerson, A.S. (2017). Reversible control of solubility using functionalized nanoparticles. Chemical Communications, 53, 1429-1432 Link

Cui, Y., Stojakovic, J., Kijima, H., Myerson, A.S. (2016).Mechanism of Contact-Induced Heterogeneous Nucleation. Crystal Growth & Design 16 (10), 6131-6138 Link

Wang, H., Berton, P., Myerson, A.S. , Rogers R.D. (2016). Double Salt Ionic Liquids Containing the Trihexyl (tetradecyl) phosphonium Cation: The Ability to Tune the Solubility of Aromatics, Ethers, and Lipophilic Compounds. ECS Transactions 75 (15), 451-465 Link

Zhu, Z., Peng, Y., Hatton, T.A., Samrane,K., Myerson, A.S., Braatz, R.D. (2016). Crystallization of Calcium Sulphate During Phosphoric Acid Production: Modeling Particle Shape and Size Distribution. Procedia Engineering 138, 390-402 Link

Matheys,C,. Tumanova, N., Leyssens, T., Myerson, A.S. (2016). Magnetic Levitation as a Tool for separation: Separating Cocrystals from Crystalline phases of individual compounds.Crystal Growth & Design Link

Stelzer, T., Wong, S.Y., Chen, J., Myerson, A.S. (2016) Evaluation of PAT Methods for Potential Application in Small-Scale, Multipurpose Pharmaceutical Manufacturing Platforms. Organic Process Research & Development 20 (8), 1431-1438. Link

Monbaliu, J.C., Stelzer, T., Revalor, E., Weeranoppanant, N., Jensen, K.,  Myerson, A.S. (2016). Compact and Integrated Approach for Advanced End-to-End Production, Purification, and Aqueous Formulation of Lidocaine Hydrochloride. Organic Process Research & Development 20 (7), 1347-1353. Link

Cui, Y., O’Mahony, M., Jaramillo, J.J., Stelzer, T., Myerson, A.S. (2016). Custom-Built Miniature Continuous Crystallization System with Pressure-Driven Suspension Transfer. Organic Process Research & Development 20 (7), 1276-1282. Link

Badruddoza, A.Z.M., Godfrin, P.D., Myerson, A.S. ,Trout, B.L., Doyle, P.S. (2016). Core–Shell Composite Hydrogels for Controlled Nanocrystal Formation and Release of Hydrophobic Active Pharmaceutical Ingredients. Advanced healthcare materials. Link

Shim, H.M., Myerson, A.S., Koo, K.K. (2016). Molecular Modeling on the Role of Local Concentration in the Crystallization of l-Methionine from Aqueous Solution. Crystal Growth & Design. Link

Adamo, A., Beingessner, R., Behnam, M., Chen, J., Jamison, T., Jensen, K.F., Monbaliu, J.C., Myerson, A.S., Revalor, E., Snead, D., Stelzer,T., Weeranoppanant, N., Wong, S., Zhang, P. (2016). On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system. Science 352 (6281), 61-67. Link

Pons-Siepermann, C.A., Huang, S., Myerson, A.S. (2016). Purification of nitrophenols using complex-assisted crystallization. CrystEngComm. Link

Yazdanpanah, N., Myerson, A.S.,  Trout, B.L. (2016). Mathematical Modeling of Layer Crystallization on a Cold Column with Recirculation. I&EC Research Link